| Saturday, 14 August, 2021 |
| Borussia Mönchengladbach |
01:30 |
Bayern Munich |
| Augsburg 1907 |
20:30 |
TSG 1899 Hoffenheim |
| Arminia Bielefeld |
20:30 |
SC Freiburg |
| Wolfsburg |
20:30 |
VFL Bochum |
| Stuttgart |
20:30 |
Greuther Fürth |
| Union Berlin |
20:30 |
Bayer 04 Leverkusen |
| Borussia Dortmund |
23:30 |
Eintracht Frankfurt |
| Sunday, 15 August, 2021 |
| Mainz |
20:30 |
RB Leipzig |
| FC Cologne |
22:30 |
Hertha Berlin |
| Saturday, 21 August, 2021 |
| RB Leipzig |
01:30 |
Stuttgart |
| Greuther Fürth |
20:30 |
Arminia Bielefeld |
| VFL Bochum |
20:30 |
Mainz |
| Hertha Berlin |
20:30 |
Wolfsburg |
| SC Freiburg |
20:30 |
Borussia Dortmund |
| Eintracht Frankfurt |
20:30 |
Augsburg 1907 |
| Bayer 04 Leverkusen |
23:30 |
Borussia Mönchengladbach |
| Sunday, 22 August, 2021 |
| TSG 1899 Hoffenheim |
20:30 |
Union Berlin |
| Bayern Munich |
22:30 |
FC Cologne |
| Saturday, 28 August, 2021 |
| Borussia Dortmund |
01:30 |
TSG 1899 Hoffenheim |
